Tremadone by Nutriganix comes out as the clear winner with a strong combination of price and most importantly customer satisfaction. Let’s take a look at closer look at the Tremadone ingredients to see why. Please note that supporting studies are hyperlinked for ease of reference.

1. GABA – This amino acid is made in the brain and found in some foods. The inability of GABA receptors to communicate effectively in the cerebellum has been noted as the most likely cause of Essential Tremor in multiple studies. ^[1][2]
2. Valerian Root – Valerian Root enhances the message relay of neurotransmitters in the body. It has an effect similar to Benzodiazepine drugs, but carries none of the potentially dangerous side effects. ^[3]
3. Skullcap – Skullcap is known to be rich in the type of antioxidants that protect against the degeneration of healthy neurotransmitters in the brain, such as GABA. ^[4]
4. Passion Flower – Long used as a traditional remedy for anxiety, Passion Flower has performed as well as prescription drugs in double-blind studies in reducing generalized anxiety disorder. Though often underreported, generalized anxiety disorder impacts a considerable portion of people suffering from tremors. ^[5]
5. Folic Acid – This B Vitamin is used by the body to make healthy new cells and is found in specific vegatables, fruits, and nuts. Folic Acid deficiency is thought to reduce the effectiveness of neurotransmitters in the brain, which can cause a number of unwanted symptoms including depression and anxiety. ^[6]
6. B-12 with Methylcobalamin – Groups who are most prone to B-12 deficiency — like folks who suffer from fibromyalgia and alcoholism — also have a higher risk of tremors. It has been working very well in the Tremadone formulation. ^[7]
7. B-2 with Riboflavin – B-2 with Riboflavin plays a vital role in metabolism and helps the body better absorb the ingredients in the Tremadone formula.

Tremadone is an all natural supplement and no prescription is required. Many people take it with medications, but always check with your doctor first.

1. Linking Essential Tremor to the Cerebellum: Neurochemical Evidence. Marin-Lahoz J, Gironell A. http://www.ncbi.nlm.nih.gov/pubmed/26498765

2. Gaba and serotonin molecular neuroimaging in essential tremor: a clinical correlation study. Gironell A, Figueiras FP, Pagonabarraga J, Herance JR, Pascual-Sedano B, Trampal C, Gispert JD. http://www.ncbi.nlm.nih.gov/pubmed/22595620

3. Selective Interactions of Valeriana officinalis Extracts and Valerenic Acid with [3H] Glutamate Binding to Synaptic Membranes. Lisa M. Del Valle-Mojica, Yoshira M. Ayala-Marin, Carmen M. Ortiz-Sanchez, Bianca A. Torres-Hernandez, Safa Abdalla-Mukhaimer, Jose G. Ortiz. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3092575/

4. Anti-oxidative and DNA protecting effects of flavonoids-rich Scutellaria lateriflora. Lohani M, Ahuja M, Buabeid MA, Dean S, Dennis S, Suppiramaniam V, Kemppainen B, Dhanasekaran M. http://www.ncbi.nlm.nih.gov/pubmed/24354189

5. Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial. Akhondzadeh S, Naghavi HR, Vazirian M, Shayeganpour A, Rashidi H, Khani M. http://www.ncbi.nlm.nih.gov/pubmed/11679026

6. The neurology of folic acid deficiency. Reynolds EH. http://www.ncbi.nlm.nih.gov/pubmed/24365361

7. The neurology of folic acid deficiency. Reynolds EH. http://www.ncbi.nlm.nih.gov/pubmed/24365361

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